Do corticosteroids reduce postoperative pain following third molar intervention?
Sugragan Chollathit, Sirintawat Nattapong, Kiattavornchareon Sirichai, Khoo Lee Kian, Kumar K. C., Wongsirichat Natthamet,
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( Sugragan Chollathit ) - Mahidol University Faculty of Dentistry Department Oral & Maxillofacial Surgery
( Sirintawat Nattapong ) - Mahidol University Faculty of Dentistry Department Oral & Maxillofacial Surgery
( Kiattavornchareon Sirichai ) - Mahidol University Faculty of Dentistry Department Oral & Maxillofacial Surgery
( Khoo Lee Kian ) - Mahidol University Faculty of Dentistry Department Oral & Maxillofacial Surgery
( Kumar K. C. ) - Mahidol University Faculty of Dentistry Department Oral & Maxillofacial Surgery
( Wongsirichat Natthamet ) - Mahidol University Faculty of Dentistry Department Oral & Maxillofacial Surgery
Abstract
Background: Corticosteroids have been widely used by oral surgeons for reducing swelling caused by wisdom teeth surgery. However, they have not been proven to decrease pain. This study was aimed at analyzing previous studies pertaining to corticosteroids and pain reduction following wisdom teeth surgery.
Methods: The Science Direct, PubMed, and MEDLINE databases were searched for relevant journals according to a systematic search strategy (Patient Intervention Comparison Outcome Study). Randomized controlled trials published in English from 1998 to 2017 were extracted.
Results: Twenty-seven articles were included, with a total of 36 comparative cases. Methylprednisolone and dexamethasone were the most commonly used corticosteroids. Intramuscular injections of corticosteroids were optimal for pain reduction, regardless of the time of administration.
Conclusions: Corticosteroids can be used as an adjuvant for pain reduction following wisdom teeth surgery. Methylprednisolone and dexamethasone delivered via the intramuscular route is the best method for effective pain reduction. The ideal time for administration of corticosteroids is the preoperative period.
키워드
Corticosteroid; Dexamethasone; Mandible; Postoperative Pain; Surgical Removal; Third Molar
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